Journal article

Are nasal symptoms related to infections or allergies? A prospective study of atopy-prone children from birth to 2 years

CS Hosking, DJ Hill, J Thorburn, SC Dharmage

Pediatric Asthma, Allergy and Immunology | Published : 2007


The objective of this study was to determine the relationship between infections, atopic disease, and nasal symptoms in early childhood. A prospective study was conducted on a cohort of 620 atopy-prone infants from birth to 2 years. Through the first 64 weeks, telephone questionnaires were administered by interview at 4-week intervals, then at 78 weeks and 2 years of age. Information regarding various factors for the 4 weeks prior to administration of the questionnaire was documented. Skin-prick tests for six allergen extracts were performed at 6, 12, and 24 months. The association between nasal symptoms as reported by parents and markers of atopic disease and infections was examined using M..

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