Journal article

Treatment of Paget's disease of bone: A survey of clinical practice in Australia

JP Walsh, R Attewell, BGA Stuckey, MJ Hooper, JD Wark, S Fletcher, V Ferrari, JA Eisman

BONE | ELSEVIER SCIENCE INC | Published : 2008

Abstract

Consensus guidelines for the treatment of Paget's disease of bone have been published, but it is not known how closely these reflect clinical practice. We conducted a multi-centre, stratified, retrospective review of case notes of 531 subjects treated for Paget's disease of bone between 2000 and 2005 in 29 Australian centres. The subjects received 1072 courses of bisphosphonate treatment (pamidronate 363, alendronate 324, risedronate 208, tiludronate 103, zoledronic acid 69, and etidronate 5). The most recent treatment received was oral therapy in 57% of patients (alendronate 29%, risedronate 24%, and tiludronate 4%) and intravenous in 43% (pamidronate 33%, and zoledronic acid 10%). For oral..

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