Journal article

Reliability of different image analysis methods for scanning laser Doppler flowmetry

Andreas J Kreis, Thanh Nguyen, Sophie Rogers, Jie Jin Wang, Joanna Harazny, Georg Michelson, HM Omar Farouque, Tien Y Wong

CURRENT EYE RESEARCH | TAYLOR & FRANCIS INC | Published : 2008

Abstract

PURPOSE: To assess reliability and reproducibility of different analysis methods for retinal capillary flow, volume, and velocity from scanning laser Doppler flowmetry (SLDF) topography. MATERIAL AND METHODS: SLDF topography analysis using the default retinal flowmeter (HRF) were compared to that using automatic full-field perfusion image analyzer (AFFPIA) and quantified as intraclass correlation coefficients (ICC). RESULTS: The AFFPIA full-field method had the highest reliability, with ICC 0.99 for capillary flow. The reproducibility using the AFFPIA full-field method was high ICC 0.74 for capillary flow. CONCLUSIONS: The AFFPIA full-field method is highly reliable and superior to the defau..

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