Functionalised fibrils for bio-nanotechnology
Sally L Gras, Adam M Squires, Christopher M Dobson, Cait E MacPhee
2006 INTERNATIONAL CONFERENCE ON NANOSCIENCE AND NANOTECHNOLOGY, VOLS 1 AND 2 | IEEE | Published : 2006
Amyloid fibrils offer great potential as nano-materials. Functionalised fibrils assembled from peptides coupled to bioactive ligands interact specifically with cells compared to non-functionalized fibrils, suggesting that these fibrils are also promising bio-scaffolds. © 2006 IEEE.
We thank Dr Anna Tickler for peptide synthesis and mass spectrometry, Darerca Owen for cell culture facilities and Dr Filip Meersman and Professor Mike Horton for discussions. S.L.G. is funded by a Gates Cambridge Scholarship, C.M.D is funded by the Wellcome and Leverhulme Trusts and C.E.M. is a Royal Society University Research Fellow.