Journal article

Consistency and functional specialization in the default mode brain network

Ben J Harrison, Jesus Pujol, Marina Lopez-Sola, Rosa Hernandez-Ribas, Joan Deus, Hector Ortiz, Carles Soriano-Mas, Murat Yucel, Christos Pantelis, Narcis Cardoner

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | NATL ACAD SCIENCES | Published : 2008

Abstract

The notion of a "default mode of brain function" has taken on certain relevance in human neuroimaging studies and in relation to a network of lateral parietal and midline cortical regions that show prominent activity fluctuations during passive imaging states, such as rest. In this study, we perform three fMRI experiments that demonstrate consistency and specialization in the default mode network. Correlated activity fluctuations of default mode network regions are identified during (i) eyes-closed spontaneous rest, (ii) activation by moral dilemma, and (iii) deactivation by Stroop task performance. Across these imaging states, striking uniformity is shown in the basic anatomy of the default..

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