Journal article

Morphology of the corpus callosum at different stages of schizophrenia: Cross-sectional study in first-episode and chronic illness

Mark Walterfang, Amanda G Wood, David C Reutens, Stephen J Wood, Jian Chen, Dennis Velakoulis, Patrick D McGorry, Christos Pantelis

British Journal of Psychiatry | Royal College of Psychiatrists | Published : 2008


BackgroundThe shape of the corpus callosum may differ in schizophrenia, although no study has compared first-episode with established illness.AimsTo investigate the size and shape of the corpus callosum in a large sample of people with first-episode and established schizophrenia.MethodCallosal size and shape were determined using highresolution magnetic resonance imaging on 76 patients with first-episode schizophrenia-spectrum disorders, 86 patients with established schizophrenia and 55 healthy participants.ResultsThere were no significant differences in tota..

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