Non-invasive automated measurement of cardiac output during stable cardiac surgery using a fully integrated differential CO2 Fick method

Abstract

Objectives: To re-evaluate the accuracy and precision of a non-invasive method for measurement of cardiac output based on the differential CO2 Fick approach using an automated change in respiratory rate delivered by a ventilator under control by a prototype measurement system. Methods: Twenty-four patients during coronary artery bypass surgery, pre- and postcardiopulmonary bypass were recruited. After routine cannulation including pulmonary artery catheter, relaxant general anesthesia was induced. After hemodynamic and ventilatory stability were achieved, simultaneous paired measurements were made by the differential Fick method and by bolus thermodilution. Measurements were generated by ind..