Journal article

No evidence for interaction between MAOA and childhood adversity for antisocial behavior

Zoe Prichard, Andrew Mackinnon, Anthony F Jorm, Simon Easteal

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS | WILEY-LISS | Published : 2008

Abstract

Previous reports have identified an interaction between an MAOA promoter polymorphism and childhood adversity for antisocial behavioral outcomes in males. This study attempted to replicate this finding in an Australian community survey of 1,002 Caucasian men aged 20-24 years. Greater childhood adversity was associated with later antisocial behavior, but no association was observed between MAOA genotype and antisocial behavior, and no interaction was found between childhood adversity and MAOA genotype for antisocial behavior. This study does not support previous reports of an interaction between MAOA genotype and childhood adversity for antisocial behavior in males.