Mirror-symmetrical populations of wide-field amacrine cells of the macaque monkey retina

Abstract

Retinas of macaque monkeys were immunostained for glycogen Phosphorylase (glypho). Glypho was localized to regular and displaced amacrine cells. Their processes occupied two narrow strata within the inner plexiform layer (IPL). The labeling pattern is reminiscent of cholinergic amacrine cells; however, double immunostaining of the retinas for choline acetyl-transferase and glypho revealed two different cell populations. Intracellular injection of DiI showed that glypho-immunoreactive amacrine cells are wide-field amacrine cells with straight, radially oriented, and sparsely branched dendrites. The density of the cells increased from ∼70/mm2 in the peripheral retina to ∼700/mm2 in the central..