Journal article

A novel stimulus artifact removal technique for high-rate electrical stimulation

Leon F Heffer, James B Fallon

JOURNAL OF NEUROSCIENCE METHODS | ELSEVIER SCIENCE BV | Published : 2008

Abstract

Electrical stimulus artifact corrupting electrophysiological recordings often makes the subsequent analysis of the underlying neural response difficult. This is particularly evident when investigating short-latency neural activity in response to high-rate electrical stimulation. We developed and evaluated an off-line technique for the removal of stimulus artifact from electrophysiological recordings. Pulsatile electrical stimulation was presented at rates of up to 5000 pulses/s during extracellular recordings of guinea pig auditory nerve fibers. Stimulus artifact was removed by replacing the sample points at each stimulus artifact event with values interpolated along a straight line, compute..

View full abstract

University of Melbourne Researchers