Electronic antibiotic stewardship - reduced consumption of broad-spectrum antibiotics using a computerized antimicrobial approval system in a hospital setting
KL Buising, KA Thursky, MB Robertson, JF Black, AC Street, MJ Richards, GV Brown
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | OXFORD UNIV PRESS | Published : 2008
OBJECTIVES: Antibiotic stewardship is important, but the ideal strategy for providing stewardship in a hospital setting is unknown. A practical, sustainable and transferable strategy is needed. This study evaluates the impact of a novel computerized antimicrobial approval system on antibiotic-prescribing behaviour in a hospital. Effects on drug consumption, antibiotic resistance patterns of local bacteria and patient outcomes were monitored. METHODS: The study was conducted at a tertiary referral teaching hospital in Melbourne, Australia. The system was deployed in January 2005 and guided the use of 28 restricted antimicrobials. Data were collected over 7 years: 5 years before and 2 years af..View full abstract
The National Health and Medical Research Council of Australia provides funding for the Centre for Clinical Research Excellence in Infectious Diseases. The Guidance DS project was initially funded by a grant from the Biotechnology Innovation Fund from the Commonwealth Government of Australia. Ongoing funding was provided by Melbourne Health.