Journal article
Psychosocial factors and survival of young women with breast cancer: A population-based prospective cohort study
KA Phillips, RH Osborne, GG Giles, GS Dite, C Apicella, JL Hopper, RL Milne
Journal of Clinical Oncology | AMER SOC CLINICAL ONCOLOGY | Published : 2008
Abstract
Purpose: Most women with early-stage breast cancer believe that psychosocial factors are an important influence over whether their cancer will recur. Studies of the issue have produced conflicting results. Patients and Methods: A population-based sample of 708 Australian women diagnosed before age 60 years with nonmetastatic breast cancer was observed for a median of 8.2 years. Depression and anxiety, coping style, and social support were assessed at a median of 11 months after diagnosis. Hazard ratios for distant disease-free survival (DDFS) and overall survival (OS) associated with psychosocial factors were estimated separately using Cox proportional hazards survival models, with and witho..
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Awarded by National Cancer Institute
Funding Acknowledgements
Supported by the National Health and Medical Research Council (NHMRC) of Australia (Grant No. 145604) and the United States National Institutes of Health (Grant No. RO1 CA10274001A2). The Australian Breast Cancer Family Study was supported by the NHMRC of Australia, the New South Wales Cancer Council, the Victorian Health Promotion Foundation, and the United States National Cancer Institute, National Institutes of Health (Grant No. RFA CA-95-011), and through cooperative agreements with members of the Breast Cancer Family Registry and principal investigators. K.-A. P. is supported by the Cancer Council Victoria, John Colebatch Clinical Research Fellowship. R. H. O. is supported by an NHMRC Population Health Fellow Fellowship. J. L. H. is an Australia Fellow of the NHMRC and a Victorian Breast Cancer Research Consortium Group Leader.