Journal article

Identification of novel and known ovary-speciftic genes including the stripe-faced ZP2, in a marsupial, dunnart

Phil Chi Khang Au, Jane Whitley, David Vaux, Lynne Selwd, Mary Familar

MOLECULAR REPRODUCTION AND DEVELOPMENT | WILEY | Published : 2008

Abstract

During the early stages of oogenesis, oocyte-specific factors, synthesized by and stored within the oocyte, play critical roles during oogenesis, folliculogenesis, fertilization and early embryonic development in the mouse. The identification of marsupial maternal factors, expressed specifically in the ovary or oocyte, may provide an insight into the conserved evolutionary mechanisms that drive mammalian oocyte development to cleavage stages. In this study, 10 clones including dunnart ZP2 and c-mos, isolated by cDNA representational difference analysis, were validated by RT-PCR for ovary-specific expression. This novel combination of techniques to isolate ovary-specific genes has identified ..

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University of Melbourne Researchers