Journal article

Vascular Changes After Intra-bleb Injection of Bevacizumab

Michael A Coote, Jonathan B Ruddle, Queena Qin, Jonathan G Cromston

JOURNAL OF GLAUCOMA | LIPPINCOTT WILLIAMS & WILKINS | Published : 2008

Abstract

PURPOSE: To illustrate changes in bleb vascularity after subconjunctival bevacizumab injection. METHODS: Longitudinal changes in bleb vascularity were followed over 6 months pre and postbevacizumab injection. RESULTS: Bleb vascularity associated with increased scarring activity was observed 10 days postcataract surgery in an eye that had undergone trabeculectomy 3 months previously. A single subconjunctival avastin injection led to a dramatic reduction in bleb vascularity for 6 weeks. With continued steroids, a diffuse, healthy, well functioning bleb with minimal scar tissue was present at 6 months. CONCLUSIONS: Subconjunctival injection of bevacizumab reduced bleb vascularity and may provid..

View full abstract