Lung volume and cardiorespiratory changes during open and closed endotracheal suction in ventilated newborn infants

Abstract

Objectives: To compare change in lung volume (ΔVL), using respiratory inductive plethysmography, time to recover pre-suction lung volume (trec) and the cardiorespiratory disturbances associated with open suction (OS) and closed suction (CS) in ventilated infants. Design: Randomised blinded crossover trial. Setting: Neonatal intensive care unit. Patients: Thirty neonates, 20 receiving synchronised intermittent mandatory ventilation (SIMV) and 10 high-frequency oscillatory ventilation (HFOV, four receiving muscle relaxant). Interventions: OS and CS were performed, in random order, on each infant using a 6FG catheter at -19 kPa for 6 seconds and repeated after 1 minute. Outcome measures: ΔVL, o..