Journal article
IS DEPRESSION ASSOCIATED WITH MICROVASCULAR DISEASE IN PATIENTS WITH TYPE 2 DIABETES?
Tan Nguyen Thanh, Tien Y Wong, FM Amirul Islam, Larry Hubbard, Jacqueline Miller, Ebrahim Haroon, Christine Darwin, Barbara Esser, Anand Kumar
DEPRESSION AND ANXIETY | WILEY-BLACKWELL | Published : 2008
DOI: 10.1002/da.20427
Abstract
We hypothesize that late-life depression is a manifestation of microvascular disease in patients with type 2 diabetes. We conducted a clinic-based cross-sectional study, comparing retinal vascular caliber, a marker of microvascular disease, in participants with type 2 diabetes with major depression (n=34), without depression (n=27) and healthy non-diabetic controls (n=38). Retinal vascular caliber was measured from digital retinal photographs using a validated computer-assisted method. After adjusting for age and gender, there was a trend of increasing retinal arteriolar caliber from healthy controls (132.6 microm), to diabetic patients without depression (139.2 microm), and diabetic patient..
View full abstractGrants
Awarded by National Institute of Health
Awarded by National Health and Medical Research Council, Australia
Awarded by NATIONAL INSTITUTE OF MENTAL HEALTH
Funding Acknowledgements
Contract grant sponsor: National Institute of Health; Contract grant numbers: R01-MH-63674, MH-55115, MH-61567, MH-02043; Contract grant sponsor: General Clinical Research Center; Contract grant sponsor: National Health and Medical Research Council, Australia; Contract grant numbers: 350448; Contract grant sponsor: Sylvia and Charles Viertel Clinical Investigator Award.