Changes in Abdominal Obesity and Age-Related Macular Degeneration The Atherosclerosis Risk in Communities Study
Anna Peeters, Dianna J Magliano, June Stevens, Bruce B Duncan, Ronald Klein, Tien Y Wong
ARCHIVES OF OPHTHALMOLOGY | AMER MEDICAL ASSOC | Published : 2008
OBJECTIVE: To examine the association between changes in waist-hip ratio (WHR), a measure of abdominal obesity, and age-related macular degeneration (AMD). METHODS: A total of 12 515 persons from a population-based cohort study, aged 45 to 64 years in 1987 to 1989, were followed up over 6 years. The percentage change in WHR during follow-up was ranked into sex-specific deciles; an increase in WHR was defined as the top 10% of change and a decrease in WHR as the bottom 10%. The association of increased or decreased WHR and presence of AMD at follow-up was determined using logistic regression adjusting for potential confounders. RESULTS: The average change in WHR was an increase of 2%, ranging..View full abstract
Awarded by National Heart, Lung, and Blood Institute
Awarded by DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS
Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Atherosclerosis Risk in Communities Study is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute contracts N01-HC-55015, N01-HC-55016, N01-HC-55018, N01-HC-55019, N01-HC-55020, N01-HC-55021, and N01-HC-55022. Additional support was provided by a VicHealth Research Fellowship (Dr Peeters) and the National Heart Foundation, Australia (Dr Wong).