Journal article
Diaryl ether synthesis in supercritical carbon dioxide in batch and continuous flow modes
JK Lee, MJ Fuchter, RM Williamson, GA Leeke, EJ Bush, IF McConvey, S Saubern, JH Ryan, AB Holmes
Chemical Communications | ROYAL SOC CHEMISTRY | Published : 2008
DOI: 10.1039/b808374f
Abstract
A high yielding, batch mode synthesis of diaryl ethers and sulfides by an SNAr fluoride-mediated process in scCO2 has been developed; the use of a polymer-supported imidazolium fluoride reagent in batch mode led to the development of a fixed-bed continuous flow process, with high conversions. © The Royal Society of Chemistry.
Grants
Funding Acknowledgements
We thank AstraZeneca (UK), the Overseas Research Students Awards Scheme (Universities UK), the Cambridge Overseas Trust, the Engineering and Physical Sciences Research Council (UK), the Australian Research Council, VESKI and CSIRO (Australia) for financial support. This project was carried out with partial support from the Materials World Network (NSF/ARC).