Obstetric Events as a Risk Factor for Febrile Seizures: A Community-Based Twin Study
Ingo Helbig, Kate M Lawrence, Mary M Connellan, Yvonne Torn-Broers, Lata Vadlamudi, Jazmin Eckhaus, Roger L Milne, John L Hopper, Samuel F Berkovic
TWIN RESEARCH AND HUMAN GENETICS | CAMBRIDGE UNIV PRESS | Published : 2008
Adverse events during the perinatal period have traditionally been thought to contribute to the risk of febrile seizures although an association has not been found in large epidemiological studies. Disease-discordant twins provide a means to assess the role of non-shared environmental factors while matching for confounding factors and avoiding difficulties of epidemiological studies in singletons. This study aimed to examine the association of obstetric events and febrile seizures in a community-based twin study. Twenty-one twin pairs discordant for febrile seizures were ascertained from a community-based twin register. Obstetric events were scored using the McNeil-Sjöström Scale for Obstetr..View full abstract
This work was supported by the National Health and Medical Research Council of Australia (SFB) and the Australian Twin Registry (JLH). We report no conflicts of interest.