Nonlinear interactions of high-frequency oscillations in the human somatosensory system
U Jaros, B Hilgenfeld, S Lau, G Curio, J Haueisen
CLINICAL NEUROPHYSIOLOGY | ELSEVIER IRELAND LTD | Published : 2008
OBJECTIVE: The source of somatosensory evoked high-frequency activity at about 600 Hz is still not completely clear. Hence, we aimed to study the influence of double stimulation on the human somatosensory system by analyzing both the low-frequency activity and the high-frequency oscillations (HFOs) at about 600 Hz. METHODS: We used median nerve stimulation at seven interstimuli intervals (ISIs) with a high time resolution between 2.4 and 4.8 ms to investigate the N15, N20 and superimposed HFOs. Simultaneously, the electroencephalogram and the magnetoencephalogram of 12 healthy participants were recorded. Subsequently, the source analysis of precortical and cortical dipoles was performed. RES..View full abstract
Awarded by German Research Foundation
Awarded by SFB
This work was supported by the German Research Foundation (DFG Wi 1166/6-1/2, Ha 2899/3-1, BMBF 01 GQ 0703) and by a grant of the IZKF (Interdisziplinares Zentrum fur klinische Forschung) of the University Hospital Jena, Germany. G.C. was supported by SFB 618-134.