Journal article

Nonlinear interactions of high-frequency oscillations in the human somatosensory system

U Jaros, B Hilgenfeld, S Lau, G Curio, J Haueisen

CLINICAL NEUROPHYSIOLOGY | ELSEVIER IRELAND LTD | Published : 2008

Abstract

OBJECTIVE: The source of somatosensory evoked high-frequency activity at about 600 Hz is still not completely clear. Hence, we aimed to study the influence of double stimulation on the human somatosensory system by analyzing both the low-frequency activity and the high-frequency oscillations (HFOs) at about 600 Hz. METHODS: We used median nerve stimulation at seven interstimuli intervals (ISIs) with a high time resolution between 2.4 and 4.8 ms to investigate the N15, N20 and superimposed HFOs. Simultaneously, the electroencephalogram and the magnetoencephalogram of 12 healthy participants were recorded. Subsequently, the source analysis of precortical and cortical dipoles was performed. RES..

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