Whole Globe Enucleation Versus In Situ Excision for Donor Corneal Retrieval-A Prospective Comparative Study
Vishal Jhanji, Radhika Tandon, Namrata Sharma, Jeewan S Titiyal, Gita Satpathy, Rasik B Vaipayee
CORNEA | LIPPINCOTT WILLIAMS & WILKINS | Published : 2008
PURPOSE: The purpose of this study was to compare the results after changing from conventional whole globe enucleation to in situ excision of donor corneas. METHODS: Donor corneal tissue retrieved by enucleation (n = 50) and in situ excision (n = 50) was quantitatively evaluated prospectively, and the main parameters evaluated were endothelial cell counts, ultrasonic corneal pachymetry, microbial contamination, graft clarity, and postoperative median visual acuity at the end of 3 months. RESULTS: Mean preoperative donor endothelial cell densities were 2174 +/- 123 and 2132 +/- 149 cells per millimeter square after enucleation and in situ excision, respectively (P = 0.13). The preoperative di..View full abstract
The authors are grateful to Dr. R. M. Pandey, PhD, head of the Department of Biostatistics, AIIMS and senior program consultant INCLEN Trust International, for his help with statistical methods, analysis, and interpretation.