Journal article

Early intervention for adolescents with borderline personality disorder using cognitive analytic therapy: randomised controlled trial

Andrew M Chanen, Henry J Jackson, Louise K McCutcheon, Martina Jovev, Paul Dudgeon, Hok Pan Yuen, Dominic Germano, Helen Nistico, Emma McDougall, Caroline Weinstein, Verity Clarkson, Patrick D McGorry



BACKGROUND: No accepted intervention exists for borderline personality disorder presenting in adolescence. AIMS: To compare the effectiveness of up to 24 sessions of cognitive analytic therapy (CAT) or manualised good clinical care (GCC) in addition to a comprehensive service model of care. METHOD: In a randomised controlled trial, CAT and GCC were compared in out-patients aged 15-18 years who fulfilled two to nine of the DSM-IV criteria for borderline personality disorder. We predicted that, compared with the GCC group, the CAT group would show greater reductions in psychopathology and parasuicidal behaviour and greater improvement in global functioning over 24 months. RESULTS: Eighty-six p..

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Awarded by Victorian Health Promotion Foundation, Melbourne, Australia

Awarded by National Health and Medical Research Council Canberra, Australia

Funding Acknowledgements

The authors thank all participants in this study and the staff of ORYGEN Youth Health. Particular thanks go to or Anthony Ryle, Dr Ian Kerr, Ms Eva Burns-Lundgren, Dr Dawn Bennett, Dr Jackie Withers and the Association for Cognitive Analytic Therapy (UK) for training and supervision in cognitive analytic therapy, Thanks also go to Associate Professor John Gleeson for Supervision of standardised good clinical care, Dr Andrew Court for independent psychiatric assessments, Dr Carol Hulbert, Ms Helen Mildred and Dr Denise Chairman for advice on the implementation of the study and to Professor Anthony Jorm and Dr Sarah Hetrick for comments on an earlier version of this manuscript. This work was supported by grants 98-0198 from the Victorian Health Promotion Foundation, Melbourne, Australia and grant 990748 from the National Health and Medical Research Council Canberra, Australia, The ORYGEN Research Centre is supported by an unrestricted grant from the Colonial Foundation, Melbourne, Australia.