Pattern of lifetime Axis I morbidity among a treated sample of first-episode psychosis patients

Abstract

Background: While the problem of significant comorbidity in first-episode psychosis (FEP) is well known, little is known about the pattern of onset of disorder prior to and during FEP. The current study examined Axis I psychiatric comorbidity in 62 people being treated for FEP. Method: Morbidity in the years prior to the diagnosis of psychosis was assessed retrospectively, while comorbidities during the 15 months after psychosis diagnosis were investigated prospectively via structured clinical interview. Results: Prevalence of morbidity was high, with 84% of patients having an Axis I psychiatric disorder during at least one phase (i.e. either prior to, during or following the FEP). Sixty-nin..