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Journal article

Intracellular copper deficiency increases amyloid-ss secretion by diverse mechanisms

Michael A Cater, Kelly T McInnes, Qiao-Xin Li, Irene Volitakis, Sharon La Fontaine, Julian FB Mercer, Ashley I Bush

Biochemical Journal | PORTLAND PRESS LTD | Published : 2008

DOI: 10.1042/BJ20080103

University of Melbourne Researchers

Qiao-Xin Li's Profile Picture
Qiao-Xin Li Author Melbourne Medical School

Ashley Bush's Profile Picture
Ashley Bush Author Florey Department of Neuroscience and Mental Health

Related Projects (1)

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THE ROLE OF AMYLOID PROTEIN PRECURSOR IN MAMMALIAN COPPER TRANSPORT

The knowledge gained from this investigation will help us to develop new medicines for the treatment of debilitating and ever more prevalent..

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Citation metrics

62Web of Science
68Scopus
64Dimensions

Keywords

In-Vivo
Brain
Amyloid Beta-Protein Precursor
Sequence Homology, Amino Acid
Menkes Protein (atp7a)
Fibroblasts
Copper
Metal-Binding
Neurons
Biochemistry & Molecular Biology
Science & Technology
Protein Biosynthesis
Transcription, Genetic
Transgenic Mice
Humans
Alzheimer'S Disease (ad)
Amyloid Precursor Protein (app)
Intracellular Fluid
Signal Transduction
Neuron
Amyloid Precursor Protein Secretases
Alzheimers-Disease
Oxidative Stress
A-Beta
Amino Acid Sequence
Precursor-Protein
Cells, Cultured
Life Sciences & Biomedicine
Amyloid Beta-Peptides
Protein Processing, Post-Translational
Amyloid
Gene Expression Regulation
Peptide
Nerve Tissue Proteins
Molecular Sequence Data
Hippocampal-Neurons

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