Journal article

Plasma apolipoprotein E is decreased in schizophrenia spectrum and bipolar disorder

Brian Dean, Alison Digney, Suresh Sundram, Elizabeth Thomas, Elizabeth Scarr

PSYCHIATRY RESEARCH | ELSEVIER IRELAND LTD | Published : 2008

Abstract

We have shown that plasma apolipoprotein E is significantly decreased in treatment-free subjects with schizophrenia spectrum and bipolar disorder but increases after treatment in bipolar disorder. Levels of apolipoprotein D were not changed by treatment. Hence changed apolipoprotein E could be involved in abnormalities in lipid homeostasis in some subjects with psychiatric diseases.