Journal article

Regional pulmonary veno-occlusion: A newly identified lesion of equine exercise-induced pulmonary hemorrhage

KJ Williams, FJ Derksen, H de Feuter-Rupp, RR Pannirselvam, CM Steel, NE Robinson

VETERINARY PATHOLOGY | AMER COLL VET PATHOLOGIST | Published : 2008

Abstract

Exercise-induced pulmonary hemorrhage (EIPH) is common in horses following intense exertion, occurring in up to 75% of racing Thoroughbreds and Standardbreds. In spite of this, the pathogenesis of EIPH is poorly understood. In 7 racing Thoroughbred horses with EIPH, 6 sections were collected from the left and right lung, representing the cranial, middle, and caudal region of the dorsal and ventral lung (84 sites total). Grossly, both right and left lungs had numerous dark brown to blue-black foci along the caudodorsal visceral pleura. Tissue sections were stained with hematoxylin-eosin, Masson's trichrome, and Prussian blue. Verhoeff Van Gieson and immunohistochemistry for alpha-smooth muscl..

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University of Melbourne Researchers