Journal article

Australian Aboriginal people and Torres Strait Islanders have an atherogenic lipid profile that is characterised by low HDL-cholesterol level and small LDL particles

DN O'Neal, LS Piers, DM Iser, KG Rowley, AJ Jenkins, JD Best, K O'Dea



AIM: To characterise lipid profiles for Australian Aboriginal people and Torres Strait Islanders. METHODS: Community-based, cross-sectional surveys in 1995-1997 including: 407 female and 322 male Australian Aboriginal people and 207 female and 186 male Torres Strait Islanders over 15 years old. A comparator of 78 female (44 with diabetes) and 148 male (73 with diabetes) non-indigenous participants recruited to clinical epidemiological studies was used. Lipids were determined by standard assays and LDL diameter by gradient gel electrophoresis. RESULTS: Diabetes prevalence was 14.8% and 22.6% among Aboriginal people and Torres Strait Islanders, respectively. LDL size (mean [95% CI (confidence ..

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Awarded by NHMRC

Funding Acknowledgements

We acknowledge the Councils, Health Services and members of the Aboriginal and Torres Strait Islander communities who participated ill this study, and Rotary Club members and patients who volunteered to participate. We thank Mr. George Dragicevic for excellent technical assistance and method development, our collaborators, Dympna Leonard. Robyn McDermott. Sabina Knight. Phillip Mills, and the many people who assisted with fieldwork and laboratory analyses. This work was funded by a grant from NHMRC (#954605). KGR was a VicHealth Public Health Research Fellow.