Microfluidic polymer multilayer adsorption on liquid crystal droplets for microcapsule synthesis
Craig Priest, Anthony Quinn, Almar Postma, Alexander N Zelikin, John Ralston, Frank Caruso
LAB ON A CHIP | ROYAL SOC CHEMISTRY | Published : 2008
Exploiting microfluidic principles, the potential for chip-based multilayer assembly for the synthesis of polymer microcapsules was investigated. We demonstrate that continuous flow microfluidic multilayer synthesis is a fast, efficient, automated alternative to conventional batch synthesis. In this work, we dispersed liquid crystal (LC) molecules (organic phase) as monodisperse droplets in an aqueous continuous phase containing the primary polymer and a suitable surfactant. The primary polymer was coadsorbed with the surfactant at the organic/aqueous interface, stabilizing the LC droplets against coalescence and providing a template for subsequent polymer adsorption. As the droplet template..View full abstract
We thank Georgina K. Such and Xioajuan Hoa for synthesis of the polymers and general discussions, John F. Quinn and Angus P. R. Johnston for discussions on systems and applications of the technique, Elvira Tjipto and Sri Sivakumar for advice on the use of LCs as a template particle, and Siow Feng Chong for experimental assistance. This work was supported by the Australian Research Council under the Special Research Centre for Particle and Material Interfaces (University of South Australia), Commonwealth Research Centre, Federation Fellowship, and Discovery Project Schemes, the ARC/NHMRC Fluorescence Applications in Biotechnology and Life Sciences Network, the Victorian STI initiative and the CRC for Polymers. The Particulate Fluids Processing Centre (The University of Melbourne) is acknowledged for infrastructure support.