Journal article

Depression: An Important Comorbidity With Metabolic Syndrome in a General Population

James A Dunbar, Prasuna Reddy, Nathalie Davis-Lameloise, Benjamin Philpot, Tiina Laatikainen, Annamari Kilkkinen, Stephen J Bunker, James D Best, Erkki Vartiainen, Sing Kai Lo, Edward D Janus



OBJECTIVE: There is a recognized association among depression, diabetes, and cardiovascular disease. The aim of this study was to examine in a sample representative of the general population whether depression, anxiety, and psychological distress are associated with metabolic syndrome and its components. RESEARCH DESIGN AND METHODS: Three cross-sectional surveys including clinical health measures were completed in rural regions of Australia during 2004-2006. A stratified random sample (n = 1,690, response rate 48%) of men and women aged 25-84 years was selected from the electoral roll. Metabolic syndrome was defined by the Third Report of the National Cholesterol Education Program Expert Pan..

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Funding Acknowledgements

This study was supported by the Australian Government Department of Health and Aging, Royal Australian College of General Practitioners, Sanofi-Aventis, Pfizer, Roche Diagnostics Australia, and Servier Laboratories.We thank Professor Kerin O'Dea, Anna Chapman, Anna Kao-Philpot, Dr. Andrew Baird, the nurses carrying out the survey, and regional hospitals providing facilities for the study.