A multinational survey of prevalence and patterns of laxative use among adults with self-defined constipation
A Wald, C Scarpignato, S Mueller-Lissner, MA Kamm, U Hinkel, I Helfrich, C Schuijt, KG Mandel
ALIMENTARY PHARMACOLOGY & THERAPEUTICS | WILEY | Published : 2008
BACKGROUND: While numerous studies report prevalence of constipation, use of laxatives is poorly understood. AIM: To conduct a survey in seven countries evaluating prevalence of constipation and laxative use in its treatment. METHODS: Thirteen thousand eight hundred seventy-nine adults [approximately 2000 each from US, UK, Germany (GE), France (FR), Italy (IT), Brazil (BR) and South Korea (SK)] completed questionnaires assessing occurrence, frequency, duration and laxative use for treating constipation. RESULTS: Overall, 12.3% of adults had constipation [range: 5% (GE) to 18% (US)] in the prior year. A greater percent of women from all countries and elderly from all except SK and BR reported..View full abstract
Declaration of personal interests: A. Wald, C. Scarpignato, S. Mueller-Lissner, M. A. Kamm and K. G. Mandel have served as speakers, consultants or as advisory board members for Boehringer Ingelheim GmbH. U. Hinkel and I. Helfrich are employees of Boehringer Ingelheim, a company manufacturing laxatives. At the time of this study, C. Schuijt was also employed at Boehringer Ingelheim. Declaration of funding interests: This study was funded in full by Boehringer Ingelheim GmbH.