Journal article
Dynamics of the mucosa-associated flora in ulcerative colitis patients during remission and clinical relapse
SJ Ott, S Plamondon, A Hart, A Begun, A Rehman, MA Kamm, S Schreiber
Journal of Clinical Microbiology | Published : 2008
DOI: 10.1128/JCM.01512-08
Abstract
The colonic mucosa-associated flora (MAF) in patients with active ulcerative colitis (UC) (n = 13) was investigated by examining 16S rRNA gene signatures during remission and relapse against levels for controls (n = 5). Baseline reduction, temporal instability, and decrease of bacterial richness toward relapse were observed for UC patients, whereas the MAF for controls was stable over time. Copyright © 2008, American Society for Microbiology. All Rights Reserved.
Grants
Funding Acknowledgements
We acknowledge funding through the BMBF (Competence Network IBD, National Genome Research Network, and Infectious Disease Network), DFG, and MFG.