Review article: new drug formulations, chemical entities and therapeutic approaches for the management of ulcerative colitis
SC Ng, MA Kamm
ALIMENTARY PHARMACOLOGY & THERAPEUTICS | WILEY | Published : 2008
BACKGROUND: Treatment options for ulcerative colitis (UC) are expanding with the development of novel drug formulations and dosing regimens and new chemical entities. Although the goals of medical therapy for UC remain unchanged, that is to induce and to maintain remission, focus has also centred on improving patient compliance, modifying the natural course of disease and healing the mucosa. AIM: To examine novel formulations, new chemical entities and novel therapeutic approaches to the management of UC. METHODS: Searches for all studies related to UC treatment in Medline and abstracts from major national and international meetings published in the last 10 years. RESULTS: 5-Aminosalicylic a..View full abstract
Declaration of personal interests: Michael Kamm has received research support from Schering Plough and Shire, has been a consultant to Shire and Ferring, and has been a speaker at meetings organised by Schering Plough, Ferring and Shire. Michael Kamm is guarantor of the paper. Declaration of funding interests: None.