Estimation of transient increases in bleeding risk associated with physical activity in children with haemophilia.
Carolyn R Broderick, Robert D Herbert, Jane Latimer, Chris Barnes, Julie A Curtin, Paul Monagle
BMC Blood Disord | Published : 2008
BACKGROUND: Although it is widely appreciated that vigorous physical activity can increase the risk of bleeding episodes in children with haemophilia, the magnitude of the increase in risk is not known. Accurate risk estimates could inform decisions made by children with haemophilia and their parents about participation in physical activity and aid the development of optimal prophylactic schedules. The aim of this study is to provide an accurate estimate of the risks of bleeding associated with vigorous physical activity in children with haemophilia. METHODS/DESIGN: The study will be a case-crossover study nested within a prospective cohort study. Children with moderate or severe haemophilia..View full abstract