Future health implications of prenatal and early-life vitamin D status
Robyn M Lucas, Anne-Louise Ponsonby, Julie A Pasco, Ruth Morley
NUTRITION REVIEWS | OXFORD UNIV PRESS INC | Published : 2008
Current or recent low vitamin D status (or proxy measures such as dietary intake or ambient ultraviolet radiation) is linked to several chronic diseases, including osteoporosis, cancers, and cardiovascular and autoimmune diseases. Low prenatal vitamin D status may also increase susceptibility to such diseases in later life via specific target organ effects and/or through changes to the developing immune system. Maternal vitamin D supplementation during pregnancy could be an important public health measure to decrease risk of a range of chronic diseases, but further research is required to clarify beneficial and adverse effects of high prenatal vitamin D.
Dr Lucas receives funding support from the Royal Australasian College of Physicians through the Cottrell Fellowship and MS Research Australia through the Macquarie Bank Foundation Fellowship.