Chemotherapy dosing strategies in the obese, elderly, and thin patient: results of a nationwide survey.
Kathryn M Field, Suzanne Kosmider, Michael Jefford, Michael Michael, Ross Jennens, Michael Green, Peter Gibbs
J Oncol Pract | Published : 2008
PURPOSE: Determining the optimal starting dose of chemotherapy (CHT) presents a considerable challenge when using body-surface area (BSA)-based dosing, particularly in obese, elderly, or thin patients. We sought to document the range of approaches employed when administering CHT to these patients. METHODS: A questionnaire was developed by a panel of oncologists and mailed to all members of the Medical Oncology Group of Australia. RESULTS: From 315 oncologists, 188 responded (response rate 59.7%). BSA-based dosing is standard practice for 176 (97.2%) of the responding oncologists. In the adjuvant disease setting, 23 (12.7%) use ideal rather than actual body weight (BW) to calculate BSA, or ch..View full abstract