2-Day versus 5-day famciclovir as treatment of recurrences of genital herpes: Results of the FaST study

Abstract

FreeText:Primary efficacy endpoint: probability of having lesions ("not lesion free") at 5.5 elapsed days after initiation of therapy. Secondary efficacy variables: proportion of relapse that were aborted (failure to progress beyond the papule stage), the time between consecutive relapses, the change from baseline in the scores for pain and other individual symptoms, and change in the total Herpes Symptom Checklist (HSC) and Herpes Outbreak Impact Questionnaire (HOIQ). Symptoms included tingling, burning, pain, aching (including backache), itching, tenderness, dysuria, painful defecation, penile or vaginal discharge, headache, tiredness, urinary frequency, and bowel frequency.AdverseEffects:..