Journal article

Skeletal growth and peak bone strength

Qingju Wang, Ego Seeman

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM | ELSEVIER SCI LTD | Published : 2008

Abstract

Bone size, shape and internal architecture, and not just bone mass, account for differences in bone strength between individuals, sexes and races. The differences in bone morphology in old age - whether an individual's bone size and mass occupy the 5th, 50th or 95th percentile - is determined early in life. Bone traits track from the position established early in life. Genetic and environmental factors establish the morphological features of bone through the cellular machinery of bone modelling and remodelling which adapts bone to its loading circumstance by modifying its size and shape and the distribution of its mass. The need for both strength for loading and lightness for mobility are ac..

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University of Melbourne Researchers