Journal article

Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

M Kvansakul, H Yang, WD Fairlie, PE Czabotar, SF Fischer, MA Perugini, DCS Huang, PM Colman

Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2008


Awarded by NHMRC

Awarded by US NCI

Awarded by ARC

Awarded by Leukemia & Lymphoma Society


Funding Acknowledgements

We thank G Hacker for the F1L cDNA; J Szarlat for computational and J Blyth and A Wardak for technical assistance; staff at the beamline ID23.1 at ESRF Grenoble for help with X-ray data collection; C3 Collaborative Crystallization Centre for assistance with crystallization; C Day, G Dewson, J Gulbis, G Hacker, M Hinds, E Lee, B Smith and I Street for discussions; and M Hinds for reagents. Our work is supported by scholarships, fellowships and grants from Cancer Council of Victoria (to PMC and WDF), NHMRC (Program Grant 257502; fellowships to DCSH, PMC and WDF), US NCI (CA80188 and CA43540), ARC (ADP0556836, LE0560722 and AB07CBT004 to MAP) and the Leukemia & Lymphoma Society (SCOR 7015-02; fellowship to MK).