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Journal article

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity

KA Sedelies, A Ciccone, CJP Clarke, J Oliaro, VR Sutton, FL Scott, J Silke, O Susanto, DR Green, RW Johnstone, PI Bird, JA Trapani, NJ Waterhouse

Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2008

DOI: 10.1038/sj.cdd.4402300

University of Melbourne Researchers

John Silke's Profile Picture
John Silke Author Medical Biology (W.E.H.I.)

Ricky Johnstone's Profile Picture
Ricky Johnstone Author The Sir Peter MacCallum Department of Oncology

Vivien Sutton's Profile Picture
Vivien Sutton Author The Sir Peter MacCallum Department of Oncology

Joseph Trapani's Profile Picture
Joseph Trapani Author The Sir Peter MacCallum Department of Oncology

Jane Oliaro's Profile Picture
Jane Oliaro Author The Sir Peter MacCallum Department of Oncology

Grants

Citation metrics

26Web of Science
30Scopus
32Dimensions

Keywords

X-Linked Inhibitor of Apoptosis Protein
B-Induced Apoptosis
Mitochondrial Membranes
Permeability
Protease
Biochemistry & Molecular Biology
Cells, Cultured
Enzyme Activation
Target-Cells
Caspases
Time Factors
Science & Technology
Lymphocyte
Humans
Bcl-2
Apoptosis
Dna Fragmentation
Transfection
Granzyme
Protease Inhibitors
Amino Acid Chloromethyl Ketones
Proto-Oncogene Proteins C-Bcl-2
Granzymes
Life Sciences & Biomedicine
Mitochondria
Caspase Inhibitors
Cysteine Proteinase Inhibitors
Dipeptides
Activation
Secretory Vesicles
Ctl
Hela Cells
Cell Culture Techniques
Cytotoxic Lymphocytes
Killer Cells, Natural
Cell Biology
Perforin
Human Granzyme-B
Cytochrome-C Release

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