A very early rehabilitation trial for stroke (AVERT): Phase II safety and feasibility

Abstract

BACKGROUND AND PURPOSE - Very early rehabilitation, with an emphasis on mobilization, may contribute to improved outcomes after stroke. We hypothesized that a very early rehabilitation protocol would be safe and feasible. METHODS - We performed a randomized, controlled trial with blinded outcome assessment. Patients at 7. There was no significant difference in the number of deaths between groups (SC, 3 of 33; VEM, 8 of 38; P=0.20). Almost all deaths occurred in patients with severe stroke. Secondary safety outcomes were similar between groups. The intervention protocol was successfully delivered, achieving VEM dose targets (double SC, P=0.003) and faster time to first mobilization (P<0.001)...