Journal article

A very early rehabilitation trial for stroke (AVERT) phase II safety and feasibility

Julie Bernhardt, Helen Dewey, Amanda Thrift, Janice Collier, Geoffrey Donnan

STROKE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2008

Abstract

BACKGROUND AND PURPOSE: Very early rehabilitation, with an emphasis on mobilization, may contribute to improved outcomes after stroke. We hypothesized that a very early rehabilitation protocol would be safe and feasible. METHODS: We performed a randomized, controlled trial with blinded outcome assessment. Patients at 7. There was no significant difference in the number of deaths between groups (SC, 3 of 33; VEM, 8 of 38; P=0.20). Almost all deaths occurred in patients with severe stroke. Secondary safety outcomes were similar between groups. The intervention protocol was successfully delivered, achieving VEM dose targets (double SC, P=0.003) and faster time to first mobilization (P<0.001). C..

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