Cardiotrophin-1 Is an Osteoclast-Derived Stimulus of Bone Formation Required for Normal Bone Remodeling
Emma C Walker, Narelle E McGregor, Ingrid J Poulton, Such Pompolo, Elizabeth H Allan, Julian MW Quinn, Matthew T Gillespie, T John Martin, Natalie A Sims
Journal of Bone and Mineral Research | WILEY | Published : 2008
Awarded by NHMRC (Australia) Program
The authors thank Dr John Wark and Susan Kantor at Department of Medicine, Royal Melbourne Hospital, for use of pQCT, Dr Bettina Holtmann and Prof Michael Sendtner, University of Wurzburg, for CT-1<SUP>-/-</SUP> mice, and Prof Gerard Karsenty, Columbia University, for the 6xOSE2 construct. We also thank staff at the Bioresources Centre, St Vincent's Health for excellent animal care. The work was supported by NHMRC (Australia) Program Grant 345401 to NAS, MTG, and TJM. NAS is supported by a NHMRC (Australia) Senior Research Fellowship.