Duration of nocturnal hypoglycemia before seizures

Abstract

OBJECTIVE - Despite a high incidence of nocturnal hypoglycemia documented by the use of continuous glucose monitoring (CGM), there are no reports in the literature of nocturnal hypoglycemic seizures while a patient is wearing a CGM device. RESEARCH DESIGN AND METHODS - In this article, we describe four such cases and assess the duration of nocturnal hypoglycemia before the seizure. RESULTS - In the cases where patients had a nocturnal hypoglycemic seizure while wearing a CGM device, sensor hypoglycemia (>60 mg/dl) was documented on the CGM record for 2.25-4 h before seizure activity. CONCLUSIONS - Even with a subcutaneous glucose lag of 18 min when compared with blood glucose measurements, g..