Journal article

Methylation of the adenomatous polyposis coli (APC) gene in human placenta and hypermethylation in choriocarcinoma cells

NC Wong, B Novakovic, B Weinrich, C Dewi, R Andronikos, M Sibson, F Macrae, R Morley, MD Pertile, JM Craig, R Saffery

Cancer Letters | ELSEVIER IRELAND LTD | Published : 2008


Funding Acknowledgements

We would like to thank Dr. Nicole Brooks and Dr. Michael Permezel for help with isolation of placental tissue and parental buccal cells. Professor Lois Salamonson (Prince Henry's Institute of Medical Research, Australia), and Professor Samuel Breit (University of NSW, Australia) for CCA and endometrial cancer cell lines, Steve Nasioulis and Dr. Desiree Du Sart for human blood cells and Drs. Patrick Western and Craig Smith for mouse placental tissue. Special thanks to Shannon Cowie for exon sequencing and protein truncation testing of the APC gene in CCA cell lines. NW is supported by a Philip Desbrow Post Doctoral Fellowship from the Leukaemia Foundation of Australia, RS and JC are supported by National Health and Medical Research Council (Australia) RD Wright Fellowships.