Journal article

Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia

Ego Seeman, Jean-Pierre Devogelaer, Roman Loren, Timothy Spector, Kim Brixen, Adam Balogh, Gerold Stucki, Jean-Yves Reginster

JOURNAL OF BONE AND MINERAL RESEARCH | AMER SOC BONE & MINERAL RES | Published : 2008

Abstract

UNLABELLED: Many fractures occur in women with moderate fracture risk caused by osteopenia. Strontium ranelate was studied in 1431 postmenopausal women with osteopenia. Vertebral fracture risk reduction of 41-59% was shown depending on the site and fracture status at baseline. This is the first report of antivertebral fracture efficacy in women with vertebral osteopenia. INTRODUCTION: Women with osteoporosis are at high risk for fracture. However, more than one half of all fractures in the community originate from the larger population at more moderate risk of fracture caused by osteopenia. Despite this, evidence for antifracture efficacy in these persons is limited. The aim of this study wa..

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University of Melbourne Researchers