Physical map of two tammar wallaby chromosomes: A strategy for mapping in non-model mammals

JE Deakin; E Koina; PD Waters; R Doherty; VS Patel; ML Delbridge; B Dobson; J Fong; Y Hu; C Van Den Hurk; AJ Pask; G Shaw; C Smith; K Thompson; MJ Wakefield; H Yu; MB Renfree; JA Marshall Graves

Journal article

Physical map of two tammar wallaby chromosomes: A strategy for mapping in non-model mammals

JE Deakin, E Koina, PD Waters, R Doherty, VS Patel, ML Delbridge, B Dobson, J Fong, Y Hu, C Van Den Hurk, AJ Pask, G Shaw, C Smith, K Thompson, MJ Wakefield, H Yu, MB Renfree, JA Marshall Graves

Chromosome Research | SPRINGER | Published : 2008

DOI: 10.1007/s10577-008-1266-y

Abstract

Marsupials are especially valuable for comparative genomic studies of mammals. Two distantly related model marsupials have been sequenced: the South American opossum (Monodelphis domestica) and the tammar wallaby (Macropus eugenii), which last shared a common ancestor about 70 Mya. The six-fold opossum genome sequence has been assembled and assigned to chromosomes with the help of a cytogenetic map. A good cytogenetic map will be even more essential for assembly and anchoring of the two-fold wallaby genome. As a start to generating a physical map of gene locations on wallaby chromosomes, we focused on two chromosomes sharing homology with the human X, wallaby chromosomes X and 5. We devised ..

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University of Melbourne Researchers

Andrew Pask Author

Geoff Shaw Author

Matthew Wakefield Author

Marilyn Renfree Author

Grants

Funding Acknowledgements

We thank Ke-Jun Wei for curation of the tammar wallaby BAC libraries, and Anthony Papenfuss and Kaighin McColl for bioinformatic tools used during this project. This project was funded by the Australian Research Council (to J.A.M.G. and M. B. R.).