Mutating the Tight-Dimer Interface of Dihydrodipicolinate Synthase Disrupts the Enzyme Quaternary Structure: Toward a Monomeric Enzyme

F Grant Pearce; Renwick CJ Dobson; Anke Weber; Laura A Lane; Margaret G McCammon; Marie A Squire; Matthew A Perugini; Geoffrey B Jameson; Carol V Robinson; Juliet A Gerrard

Journal article

Mutating the Tight-Dimer Interface of Dihydrodipicolinate Synthase Disrupts the Enzyme Quaternary Structure: Toward a Monomeric Enzyme

F Grant Pearce, Renwick CJ Dobson, Anke Weber, Laura A Lane, Margaret G McCammon, Marie A Squire, Matthew A Perugini, Geoffrey B Jameson, Carol V Robinson, Juliet A Gerrard

Biochemistry | AMER CHEMICAL SOC | Published : 2008

DOI: 10.1021/bi801094t

University of Melbourne Researchers

Renwick Dobson Author Biochemistry and Pharmacology

Matt Perugini Author Biochemistry and Pharmacology

Grants

Awarded by DTRA basic research fund

Funding Acknowledgements

This work was funded, in part, by the Royal Society of New Zealand, Marsden Fund, and, in part, by the Foundation of Research, Science and Technology via a fellowship to F.G.P. J.A.G., M.A.P., and R.C.J.D. acknowledge the DTRA basic research fund (AB07CBT004) and the ARC for part funding.