Detection of NPM1 exon 12 mutations and FLT3-internal tandem duplications by high resolution melting analysis in normal karyotype acute myeloid leukemia
Angela YC Tan, David A Westerman, Dennis A Carney, John F Seymour, Surender Juneja, Alexander Dobrovic
JOURNAL OF HEMATOLOGY & ONCOLOGY | BMC | Published : 2008
This work was supported in part by a grant from Novartis Pharmaceuticals. Michelle McBean from the Diagnostic Molecular Pathology Lab, Peter MacCallum Cancer Centre extracted the DNA samples. Lee Ping Chew provided the clinical information. Prof. Bruno Falini kindly donated the antiNPM antibody (clone 376) for immunohistochemical analysis. We also thank Michael Krypuy and Chelsee Hewitt for critical reading of this manuscript.