Journal article
Is nuclear magnetic resonance lipoprotein subclass related to diabetic retinopathy? The multi-ethnic study of atherosclerosis (MESA)
Andreas J Kreis, Tien Yin Wong, FM Amirul Islam, Ronald Klein, Barbara EK Klein, Mary Frances Cotch, Alicia J Jenkins, Steven Shea, Jie Jin Wang
DIABETES & VASCULAR DISEASE RESEARCH | SAGE PUBLICATIONS LTD | Published : 2009
Abstract
OBJECTIVE: To examine the associations between nuclear magnetic resonance (NMR) defined lipoproteins and diabetic retinopathy (DR) in a population-based sample of adults with type 2 diabetes. RESEARCH DESIGN AND METHODS: In all, 921 persons with diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA) were included. DR was assessed from retinal photographs. Lipoproteins were measured by NMR spectroscopy. RESULTS: After controlling for age, race/ethnicity, study centre and diabetes and vascular risk factors, no consistent patterns of associations between NMR-defined lipoprotein particle concentrations and subclass with DR were evident. CONCLUSION: The lack of association between NMR-defin..
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Awarded by National Heart, Lung, and Blood Institute
Awarded by NIH
Awarded by National Eye Institute
Awarded by DIVISION OF EPIDEMIOLOGY AND CLINICAL APPLICATIONS
Awarded by NATIONAL EYE INSTITUTE
Awarded by NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Funding Acknowledgements
This research was supported by contracts N01-HC-95159 to N01-HC-95165 and N01-HC-95169 from the National Heart, Lung, and Blood Institute. Additional support was provided by NIH grant HL69979-03 (Klein R and Wong TY) and an intramural research programme award Z01EY000403 from the National Eye Institute, National Institutes of Health.