Journal article

Ventilation and Spontaneous Breathing at Birth of Infants with Congenital Diaphragmatic Hernia

Arjan B te Pas, C Omar F Kamlin, Jennifer A Dawson, Colm O'Donnell, Jennifer Sokol, Michael Stewart, Colin J Morley, Peter G Davis

JOURNAL OF PEDIATRICS | MOSBY-ELSEVIER | Published : 2009

Abstract

OBJECTIVE: To describe the interaction of spontaneous breaths, manual ventilation, and tidal volumes (V(T)) during stabilization of infants with congenital diaphragmatic hernia (CDH) in the delivery room. STUDY DESIGN: We studied infants with CDH receiving respiratory support at birth. Airway pressure, flow, and volume were measured, and each breath or inflation was analyzed. Each V(T) was classified as a manual inflation, a spontaneous breath, or a spontaneous breath coinciding with manual inflation on the basis of the timing of the pressure and flow waves. RESULTS: Twelve infants had 2957 breaths suitable for analysis, with spontaneous breathing in 11 infants (92%). The mean (+/-SD) propor..

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Grants

Funding Acknowledgements

C.O.F.K., J,D,, and ALP, have been beneficiaries of the Royal Women's Hospital Postgraduate Degree Scholarship. P.G.D., is partly supported by a National Health and Medical Research Council Fellowship, The authors declare no conflicts of interest